Ok, folks. Stop and think about this. Nicotine not withstanding, you are talking about chemicals. Malic acid, vanillin, etc. that are stored in warehouses, shipped in trucks, and used in other industries where they receive no special storage treatment. Recently I witnessed this same discussion and one of the participants mentioned he had recently mixed juice from bottle of concentrate he had had for 10 years and it had NOT been refrigerated. We make vaping liquids with food and perishable items names. So, being human, we equate these chemical cocktails with the thing(s) being simulated. But, they are only a bottle full of chemicals. No refrigeration required. Now, to the question of refrigerating finished vaping juices. The concentrated chemicals simulating the desired smell and taste are in a carrier of Glycerin's that are thick at room temperature. Put them in a colder environment and they get even more viscous. Try filling your tank with this liquid when it is 42 F.