Pretty vague question, which part are talking about? PWM controllers can range widely in frequency and can be used in a wide range of applications.
To talk about it in the most general terms, if you want to use a low frequency PWM controller for a PWM driven atomizer, you'd do better using an MCU since you'll need other functions as well. An MCU is perfectly suited for generating a low frequency PWM signal.
High frequency PWM is used in switching regulators to provide a purely DC output. In that case, you'd do better with a controller designed for that purpose. It' possible to design a switching regulator with a PWM controller, but it's hard to do. It's hugely easier to use a converter controller.
Converter controllers are one of those widely produced parts similar to MCUs with many optimizations to make design an easier process. Even so, high power DC-DC converter design is one of the most tricky areas of circuit design. It's really complicated to account for all the things that need to be accounted for. Everything is on the level of second order differentials so the math is crazy complicated.
You can pretty much wing it with a good simulator, but there's always an amount of bench tuning involved to get one working well and there's no guarantee. Sometimes, you have to give up on a design because it just can't meet the specs you're looking for once you get it on the bench. I've had that happen a few times already.